Delaware defeated Delaware State 35-17 in a Week 1 contest that featured several momentum swings and defensive standouts. The Fightin' Blue Hens' defense proved particularly disruptive, with Kahlil Ali recording a 45-yard interception return for a touchdown in the fourth quarter—the game's most impactful play by EPA metric.

Delaware's offense was led by quarterback Nick Minicucci, who completed 251 passing yards. Wide receiver Jake Thaw was his top target, hauling in 92 receiving yards, including a 50-yard touchdown reception in the fourth quarter.

Delaware State kept the game competitive throughout, with Kaiden Bennett connecting with Marquis Gillis for a 39-yard touchdown in the fourth quarter. Bennett also recorded a rushing touchdown for the Horseats in the third quarter.

The game saw multiple lead changes and swings in win probability, with Delaware ultimately pulling away in the final quarter. The final margin covered the 30.5-point spread, though the combined 52 points fell short of the 55.5 over-under line.